化学与材料科学学院


倪祁健


倪祁健 博士(副教授,硕士生导师)

办公室:花津校区化学与材料科学学院礼勤楼1116

实验室:花津校区化学与材料科学学院礼勤楼1123-1124

Email:qijianni@ahnu.edu.cn


教育经历

  • 2004.09-2008.07 安徽师范大学 理学学士(导师:罗时忠)

  • 2008.09-2011.07 大连理工大学 工学硕士(导师:刘春)

  • 2011.09-2015.07 德国亚琛工业大学 理学博士(导师:Dieter Enders)


工作经历

  • 2015.10-2017.10新加坡国立大学 博士后(合作导师:赵宇)

  • 2017.10 至今 安徽师范大学 化学与材料科学学院


主持项目

  • 2021.1-2023.12,国家自然科学青年基金“不对称有机小分子催化/去芳构化策略构建苯并含氮杂环类化合物”(22001010),项目负责人

  • 2019.7-2021.6 安徽省自然科学青年基金“不对称脱羧环化构建中环含氮杂环化合物”(1908085QB55),项目负责人

  • 2018年安徽省平台引才资助经费,项目负责人

  • 安徽师范大学博士科研启动基金,项目负责人


研究领域

  • 不对称过渡金属催化

  • 有机小分子催化


课题组成员

  • 在读硕士生:

    21级(张璇、张晗、邵雪城)

    22级(吴倩玲、高成、占雯燕)

    23级(程圆圆、何柳、李聪)

  • 已毕业硕士生:

18级:王旭阳(南开大学攻读博士)、曾达(江苏中烟工业有限责任公司淮阴卷烟厂)、许磊(南京工业大学攻读博士)

19级:朱智铭(华中师范大学攻读博士)、许方方、范彦君

20级:张莅蓉、姜旭华、秦唯


已发表论文

25)Zhiming Zhu, Qianling Wu, Xiaoxiao Song* and Qijian Ni*. Thermodynamic Controlled Regioselective C1-Functionalization of Indolizines with 3-Hydroxyisoindolinones via Brønsted Acid Catalyzed aza-Friedel–Crafts Reaction, J. Org. Chem. 2024, DOI: 10.1021/acs.joc.3c02522.link

24)Xuan Zhang, Xiaoxiao Song and Qijian Ni*.Organocatalytic regio- and enantioselective C1-arylation of β,γalkynyl-α-imino esters with pyrrolo[2,1-a]isoquinolines,Chem. Commun.2024,60, 831-834.link

23) Xiaoxiao Song*, Wei Qin, Xuyang Wang, Gen Luo, and Qijian Ni*.Bifunctional Squaramide-Catalyzed Asymmetric Cascade Reaction of Benzothiazoles with 2-Nitroallylic Acetates or Nitroenynes,Org. Lett.2023,25, 9164-9169.link

22)Qijian Ni*, Lirong Zhang, Zhiming Zhu, Xiaoxiao Song*.Formal [5+2] cycloaddition of ortho-indolizinyl anilines with cyclo-pentendiones: access to planar indolizine-fused azepines,Org. Chem. Front.2023,10,2526-2531.link

21)Qijian Ni*,Fangfang Xu, Xiaoxiao Song*.Diastereoselective and E/Z-Selective Synthesis of Functionalized Quinolizine Scaffolds via the Dearomative Annulation of 2-Pyridylacetates with Nitroenynes,J. Org. Chem. 2022,87, 9507-9517.link

20)Xiaoxiao Song*, Yanjun Fan, Zhiming Zhu,Qijian Ni*.Chiral Phosphoric Acid Catalyzed Asymmetric Arylation of Indolizines: Atroposelective Access to Axially Chiral 3-Arylindolizines,Org.Lett.2022,24, 2315-2320.link

19)Qijian Ni*, Zhiming Zhu, Yanjun Fan, Xiaoyun Chen, Xiaoxiao Song*.Chiral Phosphoric Acid Catalyzed Desymmetrization of Cyclopentendiones via Friedel-Crafts Conjugate Addition of Indolizines,Org.Lett.2021,23,9548-9553.link

18)Qijian Ni*, Xuyang Wang, Da Zeng, Qianling Wu, Xiaoxiao Song*.Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel-Crafts Cascade Reaction of 1,3-Nitroenynes and 3-Pyrrolyloxindoles,Org.Lett.2021,23, 2273-2278.link

17)Qijian Ni, Xiaoxiao Song, Chin Wen Png, Yongliang Zhang*, Yu Zhao*. Access to Substituted Cyclobutenes by Tandem [3,3]-Sigmatropic Rearrangement/[2+2] Cycloaddition of Dipropargylphosphonates under Ag/Co Relay Catalysis,Chem. Sci.,2020,11,12329-12335.link

16) Xiaoxiao Song*, Lei Xu,Qijian Ni*. Highly diastereoselective synthesis of 3-methylenetetrahydropyrans by palladium catalyzed oxa-[4 + 2] cycloaddition of 2-alkenylbenzothiazoles,Org. Biomol. Chem.2020,18, 6617-6621.link

15)Qijian Ni*, Xuyang Wang, Fangfang Xu, Xiaoyun Chen, Xiaoxiao Song*. Organocatalytic asymmetric [4+2] cyclization of 2-benzothiazolimines with azlactones: access to chiral benzothiazolopyrimidine derivatives,Chem. Commun.2020,56, 3155-3158.link

14) Xiaoxiao Song*, Mengjie Gu, Xiaoyun Chen, Lei Xu,Qijian Ni*. Highly Stereoselective Palladium-Catalyzed [3+2] Cycloaddition of Vinyl Epoxides and N-Benzothiazolimine,Asian J. Org. Chem.2019,8, 2180-2183.link

13) Jiayu Liao,Qijian Ni, Yu Zhao*. Catalyst-Enabled Scaffold Diversity: Highly Chemo- and Stereoselective Synthesis of Tricyclic Ketals and Triarylmethanes,Org. Lett.2017,19, 4074-4077.

12) Tao Shu,Qijian Ni, Xiaoxiao Song, Kun Zhao, Tianyu Wu, Rakesh Puttreddy, Kari Rissanen, Dieter Enders*. Asymmetric synthesis of cyclopentanes bearing four contiguous stereocenters via an NHC-catalyzed Michael/Michael/esterification domino reaction,Chem. Commun.2016,52, 2609-2611.

11)Qijian Ni, Jiawen Xiong, Xiaoxiao Song, Gerhard Raabe, Dieter Enders*. NHC-Catalyzed Activation of α,β-Unsaturated N-Acyltriazoles: An Easy Access to Dihydropyranones,Chem. Commun.2015,51, 14628-14631.

10)Qijian Ni, Jiawen Xiong, Xiaoxiao Song, Gerhard Raabe, Dieter Enders*. NHC-Catalyzed Enantioselective Annulation of Benzothiazolyl Ethyl Acetates with 2-Bromoenals,Synlett2015,26, 1465-1469.

9)Qijian Ni, Xiaoxiao Song, Jiawen Xiong, Gerhard Raabe, Dieter Enders*. Regio- and stereoselective synthesis of benzothiazolo-pyrimidinones via an NHC-catalyzed Mannich/lactamization domino reaction,Chem. Commun.2015,51, 1263-1266.

8) Lei Wang,Qijian Ni, Marcus Blümel, Tao Shu, Gerhard Raabe, Dieter Enders*. NHC-Catalyzed Asymmetric Synthesis of Functionalized Succinimides from Enals and α-Ketoamides,Chem. Eur. J.2015,21, 8033-8037.

7)Qijian Ni, Xiaoxiao Song, Gerhard Raabe, Dieter Enders*. N-Heterocyclic Carbene-Catalyzed Enantioselective Annulation of Indolin-3-ones with Bromoenals,Chem. Asian J.2014,9, 1535-1538.

6) Xiaofei Zeng,Qijian Ni, Gerhard Raabe, Dieter Enders*. A Branched Domino Reaction: Asymmetric Organocatalytic Two-Component Four-Step Synthesis of Polyfunctionalized Cyclohexene Derivatives,Angew. Chem. Int. Ed.2013,52, 2977-2980.

5)Qijian Ni, Huan Zhang, André Grossmann, Charles C. J. Loh, Carina Merkens, Dieter Enders*. Asymmetric Synthesis of Pyrroloindolones by N-Heterocyclic Carbene Catalyzed [2+3] Annulation of α-Chloroaldehydes with Nitrovinylindoles,Angew. Chem. Int. Ed.2013,52, 13562-13566. (highlighted in SYNFACTS 2014, 212)

4) Chun Liu*,Qijian Ni, Fanying Bao, Jieshan Qiu. A simple and efficient protocol for the palladium-catalyzed ligand-free Suzuki reaction at room temperature in aqueous DMF,Green Chem.2011,13, 1260-1266.

3) Chun Liu*,Qijian Ni, Jieshan Qiu*. Very Fast, Ligand-Free and Aerobic Protocol for the Synthesis of 4-Aryl-Substituted Triphenylamine Derivatives,Eur. J. Org. Chem.2011, 3009-3015.

2) Chun Liu*,Qijian Ni, Pingping Hu, Jieshan Qiu. Oxygen-promoted PdCl2-catalyzed ligand-free Suzuki reaction in aqueous media,Org. Biomol. Chem.2011,9, 1054-1060.

1) 刘春*,倪祁健, 胡萍萍, 袁浩,金子林。水溶性亚胺配体/钯催化的室温Suzuki反应,催化学报,2010,31,1277-1280.


链接

新加坡国立大学赵宇教授

德国亚琛工业大学Dieter Enders教授

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