李忠原 博士，副教授，硕士生导师 办公室: 学苑南楼五号楼 414 主页：李忠原课题组 |
♦ 学习工作经历
2021.10 - 至今 安徽师范大学
2020.04 - 2021.08 美国密西根大学，博士后 (with Prof. Nathaniel K. Szymczak and Prof. Corey Stephenson)
2018.06 - 2020.03 美国密西西比州立大学，博士后 (with Prof. Xin Cui)
2012.09 - 2017.06 中国科学技术大学，博士（导师：王官武教授）
2008.09 - 2012.07 安徽师范大学，学士（指导老师：郝二红教授）
♦ 研究兴趣
不对称催化
手性功能分子设计和合成
过渡金属催化碳氢活化
♦ 项目基金
安徽省海外留学回国人员启动项目（2026.06–2028.05）
半导体应用有机材料合成及工艺开发（2026.05–2030.04）
国家自然科学青年基金（2023.01–2025.12）
安徽省高校自然科学重点项目（2021.12–2023.12）
安徽师范大学启动基金（2021.12–2024.12）
♦课题组成员
研究生
2024级博士生 2025级博士生
吕晓娟 杨洁莹 马娟
2024级硕士生 2025级硕士生
单新新 苏彬 赵悦 刘韦吉 唐婷
本科生
2023级
邢子
2024级
王文静
♦课题组毕业生
研究生
2020级硕士
张金萍
2021级硕士
刘芳 侯富成
2022级硕士
杨洁莹
2023级博士生 2023级硕士生
张金萍 熊浦东 张雪晴 张家乐
本科生
2019级
刘柱 刘吉涛
2020级
应允义 王梓瑞 徐加快 柴思妮 左博文
2021级
徐志伟 罗晶晶 闻喻 陈奂然 江佳佳
2022级
杜雅茹 唐婉婉 程富强
♦ 代表性论文
Publications at AHNU
28. Juan Ma, Zi Xing, Yuefei Hu, Ye Liu*, Zhong-Yuan Li*. "Organocatalytic Enantioselective Synthesis of Boron-, Nitrogen-, and Sulfur-Stereogenic Compounds" Adv. Synth. Catal. 2026, 368, e70626. (Invited Review)
link：https://advanced.onlinelibrary.wiley.com/doi/10.1002/adsc.70626
27. Jia-Le Zhang, Juan Ma, Luying Guo, Yuefei Hu, Shiqing Huang*, Erhong Hao*, Zhong-Yuan Li*. "Construction of Boron-Stereogenic BODIPYs through Organo-Catalyzed Enantioselective Formal C(sp2)-O/O-H Metathesis" Nat. Commun. 2026, 17, 6308.
link：https://www.nature.com/articles/s41467-026-72860-4
26. Jin-Ping Zhang, Wei-Ji Liu, Yuefei Hu, Erhong Hao*, Zhong-Yuan Li*. "Construction of Chiral 1,2-Azaborines via Rhodium-Catalyzed Enantioselective Carbene N–H Bond Insertion" Org. Lett. 2026, 28, 394–399.
link：https://pubs.acs.org/doi/10.1021/acs.orglett.5c04827
25. Juan Ma,† Luying Guo,† Xue-Qing Zhang, Wan-Wan Tang, Xing Guo, Zhengxin Kang, Lijuan Jiao, Erhong Hao*, Zhong-Yuan Li*. "Enabling Construction of Boron-Stereogenic Formyl BODIPYs via N-Heterocyclic Carbene-Catalyzed Enantioselective Esterification" JACS Au 2025, 5, 2837–2848.
link：https://pubs.acs.org/doi/10.1021/jacsau.5c00425
24. Xue-Qing Zhang, Xiao-Juan Lv, Luying Guo, Juan Ma, Bin Su, Yuefei Hu, Lijuan Jiao, Zhong-Yuan Li*, Erhong Hao*. "Phase-Transfer-Catalyst Enabled Enantioselective C–N Coupling to Access Chiral Boron-Stereogenic BODIPYs" Nat. Commun. 2025, 16, 2735.
link：https://www.nature.com/articles/s41467-025-58117-6
23. Jie-Ying Yang, Ya-Ru Du, Fu-Qiang Cheng, Kun An, Yuefei Hu*, Zhong-Yuan Li*. "Construction of Axially Chiral Dialdehydes via Rhodium-Catalyzed Enantioselective C−H Amidation" Angew. Chem. Int. Ed. 2025, 64, e202421412.
link：https://doi.org/10.1002/anie.202421412
22. Juan Ma, Xue-Qing Zhang, Wan-Wan Tang, Lijuan Jiao, Yuefei Hu, Erhong Hao*, Zhong-Yuan Li*. "Synthesis and Characterization of Red to Near-Infrared Chiral Boron-Stereogenic α-Alkenyl BODIPYs" J. Porphyr. Phthalocya. 2025, 29, A–G.
link：https://doi.org/10.1142/S1088424625500178
21. Jingjing Cao,† Jin-Ping Zhang,† Fan Zhang, Zhengxin Kang, Lijuan Jiao, Zhong-Yuan Li*, Erhong Hao* "A Catalytic Enantioselective Suzuki Coupling for the Modular Construction of Axially Chiral BODIPYs with Bright Solid-State Emission" Org. Lett. 2025, 27, 173–179.
link：https://pubs.acs.org/doi/10.1021/acs.orglett.4c04123
20. Hua Wang, Luying Guo, Huiquan Zuo, Long Wang, Xing Guo, Zhengxin Kang, Zhong-Yuan Li*, Lijuan Jiao, Erhong Hao*. "Base-Promoted Regioselective Synthesis of α-Amino BODIPYs through Cross-Dehydrogenative Coupling with Anilines" Eur. J. Org. Chem. 2024, 27, e202400660.
link：https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202400660
19. Fan Lv, Shuangshuang Zhu, Zhong-Yuan Li*, Wangfei Wang, Hua Wang, Lijuan Jiao, Erhong Hao*. "Enabling Regioselective Synthesis of α-Methyl BODIPYs via H2O2/DMSO-Promoted Direct Methylation" Adv. Synth. Catal. 2024, 366, 3153–3159.
link：https://advanced.onlinelibrary.wiley.com/doi/10.1002/adsc.202400346
18. Fu-Cheng Hou, Jia-Le Zhang, Zi-Rui Wang, Zhong-Yuan Li*. "Rhodium-Catalyzed Three-Component C(sp3)/C(sp2)–H Activation Enabled by a Two-Fold Directing Group Strategy" Chem. Commun. 2024, 60, 5634–5637.
link：https://pubs.rsc.org/en/content/articlehtml/2024/cc/d4cc00827h
17. Long Wang, Cheng Cheng, Zhong-Yuan Li*, Xing Guo, Qinghua Wu*, Erhong Hao, Lijuan Jiao*. "Nucleophilic Aromatic Substitution (SNAr) as an Approach to Challenging Nitrogen-Bridged BODIPY Oligomers" Org. Lett. 2024, 26, 3026–3031.
link：https://pubs.acs.org/doi/10.1021/acs.orglett.4c00669
16. Zhong-Yuan Li*, Fang Liu, Heng Li, Xing Guo, Lijuan Jiao, Erhong Hao*. "Rhodium-Catalyzed Two-Fold, Regioselective and Enantioselective C–H Activation: an Efficient Strategy to Chiral Single-Benzene-Based Fluorophores" Org. Lett. 2024, 26, 444–449.
link：https://pubs.acs.org/doi/10.1021/acs.orglett.3c03467
15. Dandan Wang, Long Wang, Xing Guo, Xiankang Zhang, Juan Ma, Zhengxin Kang, Zhong-Yuan Li*, Lijuan Jiao*, Erhong Hao*. "Visible-Light-Induced Direct Photoamination of BODIPY Dyes with Aqueous Ammonia" Org. Lett. 2023, 25, 7650–7655.
link：https://pubs.acs.org/doi/10.1021/acs.orglett.3c02962
14. Fan Lv, Xing Guo, Zhong-Yuan Li*, Qinghua Wu, Juanjie Chen, Changjiang Yu, Lijuan Jiao*, Erhong Hao*. "Copper-Catalyzed α-Selective Cross-Dehydrogenative Coupling of BODIPY Dyes with Aldehydes: A New Route to Acylated BODIPYs and Dipyrromethenes" Dyes Pigments 2023, 210, 111030.
link：https://www.sciencedirect.com/science/article/pii/S0143720822009524
13. Zhong-Yuan Li*, Jin-Ping Zhang, Yun-Yi Ying, Dong Yan, Lijuan Jiao, Erhong Hao*. "Rhodium-Catalyzed Tandem C–H Annulation Enabled by Transient Directing Group Strategy and Sequential Nucleophilic Substitution" Org. Lett. 2022, 24, 7888–7893.
link：https://pubs.acs.org/doi/10.1021/acs.orglett.2c02853
12. Xinyue Wu, Guoyong Xu, Weiqing Lu, Zhong-Yuan Li*, Shengyu Dai*. "Ethylene (Co)oligomerization in Alkane Solvents Facilitated by Rigid-flexible Double-layer Steric Strategy" Eur. Polym. J. 2022, 177, 111459.
Before AHNU
11. Alex M. Davies, Zhong-Yuan Li, Corey R. J. Stephenson*, and Nathaniel K. Szymczak*.“Valorization of Ethanol: Ruthenium-Catalyzed Guerbet and Sequential Functionalization Processes” ACS Catal. 2022, 12, 6729–6736.
10. Zhong-Yuan Li, Hetti Handi Chaminda Lakmal, Xiaolin Qian, Zhenyu Zhu, Bruno Donnadieu, Sarah J. McClain, Xue Xu, and Xin Cui*. “Ruthenium-Catalyzed Enantioselective C–H Functionalization: A Practical Access to Optically Active Indoline Derivatives” J. Am. Chem. Soc. 2019, 141, 15730−15736.
9. Zhong-Yuan Li, Hetti Handi Chaminda Lakmal, Xin Cui*. “Enabling Catalytic Arene C–H Amidomethylation via Bis(tosylamido)methane as a Sustainable Formaldimine Releaser” Org. Lett. 2019, 21, 3735−3740.
8. Zhong-Yuan Li, Kun Jing, Qi-Li Li, and Guan-Wu Wang*. “Palladium-Catalyzed Decarboxylative Coupling of Potassium Oxalate Monoester with 2-Aryloxypyridines” Acta. Chim. Sinica. 2019, 77, 729−734. (Invited Article)
7. Zhong-Yuan Li, Liang Li, Qi-Li Li, Kun Jing, Hui Xu, and Guan-Wu Wang*. “Ruthenium-Catalyzed meta-Selective C–H Mono- and Difluoromethylation of Arenes through ortho-Metalation Strategy” Chem. Eur. J. 2017, 23, 3285–3290.
6. Zhong-Yuan Li, and Guan-Wu Wang*. “Palladium-Catalyzed Decarboxylative Ortho-Ethoxycarbonylation of O Methyl Ketoximes and 2 Arylpyridines with Potassium Oxalate Monoester” Org. Lett. 2015, 17, 4866−4869.
5. Zhong-Yuan Li, Dan-Dan Li, and Guan-Wu Wang*. “Palladium-Catalyzed Decarboxylative Ortho Acylation of Azobenzenes with α Oxocarboxylic Acids” J. Org. Chem. 2013, 78, 10414–10420.
4. Kun Jing, Zhong-Yuan Li, and Guan-Wu Wang*. “Direct Decarboxylative Meta-Selective Acylation of Arenes via an Ortho-Ruthenation Strategy” ACS Catal. 2018, 8, 11875−11881.
3. Qi-Li Li, Zhong-Yuan Li, Guan-Wu Wang*. “Palladium-Catalyzed Decarboxylative ortho-Acylation of Anilines with Carbamate as a Removable Directing Group” ACS Omega 2018, 3, 4187−4198.
2. Kun Jing, Jia-Ping Yao, Zhong-Yuan Li, Qi-Li Li, Hao-Sheng Lin, Guan-Wu Wang*. “Palladium-Catalyzed Decarboxylative ortho-Acylation of Benzamides with α-Oxocarboxylic Acids” J. Org. Chem. 2017, 82, 12715–12725.
1. Dan-Dan Li, Zhong-Yuan Li, Guan-Wu Wang*. “A Catalyst-Free Approach to Construct C−C Bond Initiated by N−O Bond Cleavage under Thermal Heating Conditions” J. Org. Chem. 2015, 80, 190−195.